Catalog |
BCC-005 |
Product Name |
HBTU;O-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluorophosphate |
CAS |
94790-37-1 |
EINECS |
423-020-5 |
Molecular Formula |
C11H16F6N5OP |
Molecular Weight |
379.24 |
Appearance |
White or pale yellow crystalline powder |
Assay |
≥99.0% |
Water |
≤0.30% |
Melting Point |
≥202℃ |
Molecular structure |
|
HBTU is a high-performance coupling reagent renowned for its efficiency in facilitating amide and peptide bond formation. As a uronium-type activator, it ensures minimal racemization and high reaction yields, making it indispensable in peptide synthesis, medicinal chemistry, and biopharmaceutical development.
Enhanced Reactivity
Accelerates coupling reactions under mild, energy-efficient conditions.
01
Low Epimerization Risk
Preserves stereochemical integrity in sensitive peptide synthesis (Fmoc/t-Boc strategies).
02
Pharmaceutical Grade
≥99% purity (HPLC), validated for critical applications.
03
Solvent Compatibility
Effective in DMF, DCM, and other polar aprotic solvents.
04
- Solid-phase peptide synthesis (SPPS) and oligonucleotide assembly.
- Synthesis of antibody-drug conjugates (ADCs) and small-molecule APIs.
- Bioconjugation for diagnostics and drug delivery systems.
Packaging: Provide packaging in various specifications. Store at 4°C in airtight, light-protected containers.
- Batch-specific certificates of analysis (COA) provided.
- Customizable packaging and technical support.
- Globally compliant with REACH, ISO 9001, and GMP guidelines.
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